🧬 Science Study Guide

Complete Biology Guide

Explore the science of lifeβ€”from cells to ecosystemsβ€”with clear explanations, diagrams, and practice questions.

πŸ“– What is Biology?

Biology is the scientific study of life and living organisms. It explores everything from the smallest molecules inside cells to the vast ecosystems covering our planet. Understanding biology helps us comprehend how organisms grow, function, reproduce, and interact with their environment.

Why Study Biology?

  • Medicine & Health: Understanding diseases, treatments, and human body systems
  • Environment: Conservation, climate change, and ecosystem management
  • Biotechnology: Genetic engineering, pharmaceuticals, and agriculture
  • Everyday Life: Nutrition, fitness, and understanding your own body

🎯 Key Concepts

Characteristics of Life

All living things share these fundamental characteristics:

The 8 Characteristics of Life

  • Organization: Made of one or more cells
  • Metabolism: Chemical reactions to obtain and use energy
  • Homeostasis: Maintaining stable internal conditions
  • Growth: Increase in size and/or cell number
  • Reproduction: Producing offspring
  • Response: Reacting to environmental stimuli
  • Adaptation: Evolving over generations
  • Movement: Internal or external motion
🧠 Memory Aid: MRS GREN + H
Movement, Respiration, Sensitivity, Growth, Reproduction, Excretion, Nutrition + Homeostasis

Levels of Biological Organization

Hierarchy of Life
Atom β†’ Molecule β†’ Organelle β†’ Cell β†’ Tissue β†’ Organ β†’ Organ System β†’ Organism β†’ Population β†’ Community β†’ Ecosystem β†’ Biosphere

πŸ”¬ Cell Biology

Cell Theory

The Three Principles of Cell Theory
  1. All living things are made of one or more cells
  2. The cell is the basic unit of life
  3. All cells come from pre-existing cells

Prokaryotic vs Eukaryotic Cells

Feature Prokaryotic Eukaryotic
Nucleus No (nucleoid region) Yes (membrane-bound)
Size 1-10 ΞΌm 10-100 ΞΌm
Organelles No membrane-bound Membrane-bound present
DNA Circular, in cytoplasm Linear, in nucleus
Examples Bacteria, Archaea Animals, Plants, Fungi

Key Organelles

Organelle Function Found In
Nucleus Contains DNA, controls cell activities Eukaryotes
Mitochondria Cellular respiration, produces ATP Eukaryotes
Chloroplast Photosynthesis Plants, Algae
Ribosome Protein synthesis All cells
ER (Rough) Protein processing & transport Eukaryotes
ER (Smooth) Lipid synthesis, detoxification Eukaryotes
Golgi Apparatus Modifies, packages, ships proteins Eukaryotes
Lysosome Digestion, waste breakdown Animal cells
Vacuole Storage, maintains turgor pressure Plants (large central)
Cell Wall Structural support, protection Plants, Bacteria, Fungi
🧠 Remember: "The Mighty Mitochondria"
Mitochondria = "Powerhouse of the cell" (makes ATP energy)

Photosynthesis vs Cellular Respiration

β˜€οΈ Photosynthesis (in chloroplasts)

6COβ‚‚ + 6Hβ‚‚O + Light Energy β†’ C₆H₁₂O₆ + 6Oβ‚‚

Plants convert carbon dioxide and water into glucose and oxygen using sunlight.

πŸ”₯ Cellular Respiration (in mitochondria)

C₆H₁₂O₆ + 6Oβ‚‚ β†’ 6COβ‚‚ + 6Hβ‚‚O + ATP Energy

Cells break down glucose with oxygen to release energy (ATP).

πŸ’‘ Key Insight

Photosynthesis and cellular respiration are opposite reactions! What one produces, the other uses.

🧬 Genetics

DNA Structure

The Double Helix

  • Sugar-phosphate backbone: Deoxyribose sugar + phosphate groups
  • Nitrogenous bases: Adenine (A), Thymine (T), Guanine (G), Cytosine (C)
  • Base pairing: A pairs with T, G pairs with C (complementary)
  • Hydrogen bonds: A-T has 2 bonds, G-C has 3 bonds
🧠 Base Pairing Memory Aid
"AT the Garage, Cars Go" β†’ A-T, G-C

From DNA to Protein

Central Dogma of Molecular Biology
DNA β†’ (Transcription) β†’ mRNA β†’ (Translation) β†’ Protein ↑ Replication

Key Terms

  • Replication: DNA makes a copy of itself
  • Transcription: DNA β†’ mRNA (occurs in nucleus)
  • Translation: mRNA β†’ Protein (occurs at ribosomes)
  • Codon: 3-letter mRNA code for one amino acid
  • Gene: Segment of DNA that codes for a protein

Mendelian Genetics

Key Vocabulary

  • Allele: Different versions of a gene
  • Dominant: Allele expressed when present (capital letter, e.g., B)
  • Recessive: Allele only expressed when homozygous (lowercase, e.g., b)
  • Genotype: Genetic makeup (BB, Bb, or bb)
  • Phenotype: Physical expression (what you see)
  • Homozygous: Two identical alleles (BB or bb)
  • Heterozygous: Two different alleles (Bb)
Punnett Square Example

Cross: Bb Γ— Bb (both parents heterozygous)

B b
B BB Bb
b Bb bb

Result: 1 BB : 2 Bb : 1 bb (genotypic ratio 1:2:1)

Phenotype: 3 dominant : 1 recessive (phenotypic ratio 3:1)

Evolution & Natural Selection

Darwin's Four Principles

  1. Variation: Individuals in a population have different traits
  2. Inheritance: Traits are passed from parents to offspring
  3. Selection: Some traits improve survival and reproduction
  4. Time: Over generations, favorable traits become more common

✏️ Practice Questions

Question 1 Easy
Which organelle is responsible for producing ATP through cellular respiration?
Answer: Mitochondria
Explanation: Mitochondria are called the "powerhouse of the cell" because they perform cellular respiration, converting glucose and oxygen into ATP (usable energy).
Question 2 Medium
If a DNA strand reads 5'-ATGCCA-3', what is the complementary mRNA sequence?
Step 1: Remember RNA uses Uracil (U) instead of Thymine (T)
Step 2: Apply base pairing: A→U, T→A, G→C, C→G
DNA: 5'-ATGCCA-3'
mRNA: 3'-UACGGU-5' (or written 5'-UGGCAU-3')

Answer: UACGGU

Question 3 Medium
In pea plants, tall (T) is dominant over short (t). If you cross a heterozygous tall plant (Tt) with a short plant (tt), what percentage of offspring will be short?
Step 1: Set up Punnett square for Tt Γ— tt
Step 2: Results: Tt, Tt, tt, tt
Step 3: 2 tall (Tt) : 2 short (tt)

Answer: 50% will be short

Question 4 Hard
Explain why both photosynthesis and cellular respiration are necessary for life on Earth.
Key points:
β€’ Photosynthesis produces oxygen and glucose that other organisms need
β€’ Cellular respiration converts glucose to ATP energy that all cells require
β€’ They form a cycle: photosynthesis produces Oβ‚‚ and glucose; respiration produces COβ‚‚ and Hβ‚‚O
β€’ Without photosynthesis: no oxygen or food source for most life
β€’ Without respiration: organisms couldn't extract energy from food

Together they maintain the carbon and oxygen cycles essential for life!

πŸ’‘ Tips & Tricks

πŸ” Use Analogies

Think of a cell like a city: Nucleus = City Hall, Mitochondria = Power Plants, Ribosomes = Factories, Cell Membrane = City Walls

πŸ“Š Draw Diagrams

Biology is visual! Sketch cells, DNA, food webs, and cycles. Drawing helps cement concepts in memory.

πŸ”— Connect Concepts

Biology topics are interconnected. DNA β†’ Genes β†’ Proteins β†’ Traits β†’ Evolution. Understanding relationships makes learning easier.

πŸ“ Use Punnett Squares Carefully

Always label parents clearly, use capital for dominant/lowercase for recessive, and double-check your work!

🧠 Taxonomy Order
"King Philip Came Over For Good Soup"
Kingdom β†’ Phylum β†’ Class β†’ Order β†’ Family β†’ Genus β†’ Species

⚠️ Common Mistakes to Avoid

❌ Confusing DNA and RNA

DNA has Thymine (T), RNA has Uracil (U). DNA is double-stranded, RNA is single-stranded. DNA stays in nucleus, mRNA travels out.

❌ Thinking Dominant = Common

Dominant doesn't mean "more common" or "better." It just means the trait is expressed when at least one allele is present.

❌ Mixing Up Mitosis and Meiosis

Mitosis: Body cells, 2 identical daughter cells, same chromosome number
Meiosis: Sex cells, 4 different daughter cells, half the chromosomes

❌ Forgetting Cell Differences

Plant cells have cell walls, chloroplasts, and large central vacuoles. Animal cells do NOT have these!

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πŸ“š Further Resources